This combined medication contains:

• Sildenafil Citrate (50-100mg): PDE5 inhibitor for erectile dysfunction
• Dapoxetine (30-60mg): SSRI for premature ejaculation

Dual Action:

• Improves erectile function
• Enhances ejaculatory control
• Extends sexual performance duration

Dosage & Administration

• Standard dose: 1 tablet daily (as prescribed)
• Onset: Within 60 minutes
• Duration: 4-6 hours
• Administration guidelines:
  • Take with 240ml water
  • Avoid high-fat meals before use
  • Do not exceed recommended dosage
  • Maximum frequency: Once per 24 hours

Important Precautions

Common side effects:

• Facial flushing
• Headache
• Gastrointestinal discomfort
• Nasal congestion
• Mild dizziness

Serious adverse reactions (require immediate medical attention):

• Priapism (>4 hour erection)
• Sudden hearing/vision changes
• Severe hypotension
• Syncope
• Serotonin syndrome symptoms

Absolute Contraindications

• Concurrent nitrate therapy (including recreational nitrites)
• MAOI use within past 14 days
• Severe hepatic impairment
• History of unstable angina
• Recent stroke/MI (<6 months)
• Hereditary retinal disorders

Drug Interactions

Prohibited combinations:

• All nitrate preparations
• Other PDE5 inhibitors
• Strong CYP3A4 inhibitors (ketoconazole, ritonavir)
• Serotonergic agents:
  • SSRIs/SNRIs
  • Triptans
  • Tramadol
  • Lithium

Require dose adjustment:

• Alpha-blockers
• Antihypertensives
• Moderate CYP3A4 inhibitors

Missed Dose Protocol

• Skip missed dose
• Resume normal schedule
• Never double dose

Overdose Management

Symptoms:

• Severe hypotension
• Prolonged erection
• Cardiac arrhythmias
• Serotonin toxicity

Action:

• Immediate medical attention required
• Supportive care essential
• No specific antidote available

Storage Requirements

• Temperature: 15-30°C (59-86°F)
• Protection from:
  • Moisture
  • Light
  • Heat
• Keep securely closed
• Out of children's reach

Patient Counseling Points

• Requires sexual stimulation for effect
• Does not prevent STDs/pregnancy
• Alcohol consumption not recommended
• Report any erection >4 hours immediately
• Discontinue if visual/hearing disturbances occur
• Allow 7-day washout before taking serotonergic drugs

Note: This combination therapy requires medical supervision. Regular cardiovascular assessment recommended. Not for use in women or pediatric populations.